Tetramethyl bisphenol A stimulates proliferation but inhibits fetal Leydig cell function in male rats by targeting estrogen receptor &#945; after in utero exposure.

Li, Xueyun; Meng, Fangyan; Ye, Lei; Qiao, Xinyi; Li, Jingjing; Tian, Lili; Su, Ming; Lin, Liben; Ge, Ren-Shan; Wang, Yiyan

Tetramethyl bisphenol A stimulates proliferation but inhibits fetal Leydig cell function in male rats by targeting estrogen receptor α after in utero exposure.

Li, Xueyun; Meng, Fangyan; Ye, Lei; Qiao, Xinyi; Li, Jingjing; Tian, Lili; Su, Ming; Lin, Liben; Ge, Ren-Shan; Wang, Yiyan.

Afiliação

Li X; Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Meng F; Department of pathology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Ye L; Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Qiao X; Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Li J; Department of pathology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Tian L; Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Su M; Department of pathology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Lin L; Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Ge RS; Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Wang Y; Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Environ Toxicol ; 37(11): 2743-2755, 2022 Nov.

Article em En | MEDLINE | ID: mdl-36214340

Assuntos

Retardadores de Chama; Células Intersticiais do Testículo; Animais; Compostos Benzidrílicos; Proliferação de Células; Enzima de Clivagem da Cadeia Lateral do Colesterol/metabolismo; Receptor alfa de Estrogênio/genética; Receptor alfa de Estrogênio/metabolismo; Feminino; Fluorenos; Masculino; Complexos Multienzimáticos/metabolismo; Complexos Multienzimáticos/farmacologia; Fenóis; Gravidez; Proteínas Proto-Oncogênicas c-akt/metabolismo; Ratos; Ratos Sprague-Dawley; Receptores de Ativador de Plasminogênio Tipo Uroquinase/metabolismo; Maturidade Sexual; Testículo; Testosterona

Palavras-chave

estrogen receptor α; fetal Leydig cell; proliferation; testosterone; tetramethyl bisphenol A

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Retardadores de Chama / Células Intersticiais do Testículo Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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