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Fibroblast Activation Protein Triggers Release of Drug Payload from Non-internalizing Small Molecule Drug Conjugates in Solid Tumors.
Zana, Aureliano; Galbiati, Andrea; Gilardoni, Ettore; Bocci, Matilde; Millul, Jacopo; Sturm, Theo; Stucchi, Riccardo; Elsayed, Abdullah; Nadal, Lisa; Cirillo, Martina; Roll, Wolfgang; Stegger, Lars; Asmus, Inga; Backhaus, Philipp; Schäfers, Michael; Neri, Dario; Cazzamalli, Samuele.
Afiliação
  • Zana A; R&D Department, Philochem AG, Otelfingen, Zurich, Switzerland.
  • Galbiati A; R&D Department, Philochem AG, Otelfingen, Zurich, Switzerland.
  • Gilardoni E; R&D Department, Philochem AG, Otelfingen, Zurich, Switzerland.
  • Bocci M; R&D Department, Philochem AG, Otelfingen, Zurich, Switzerland.
  • Millul J; R&D Department, Philochem AG, Otelfingen, Zurich, Switzerland.
  • Sturm T; R&D Department, Philochem AG, Otelfingen, Zurich, Switzerland.
  • Stucchi R; R&D Department, Philochem AG, Otelfingen, Zurich, Switzerland.
  • Elsayed A; R&D Department, Philochem AG, Otelfingen, Zurich, Switzerland.
  • Nadal L; Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zürich, Switzerland.
  • Cirillo M; R&D Department, Philochem AG, Otelfingen, Zurich, Switzerland.
  • Roll W; Department of Chemistry "G. Ciamician," University of Bologna, Bologna, Italy.
  • Stegger L; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.
  • Asmus I; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.
  • Backhaus P; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.
  • Schäfers M; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.
  • Neri D; European Institute for Molecular Imaging, University of Münster, Münster, Germany.
  • Cazzamalli S; Department of Nuclear Medicine, University Hospital Münster, Münster, Germany.
Clin Cancer Res ; 28(24): 5440-5454, 2022 12 15.
Article em En | MEDLINE | ID: mdl-36215129
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Imunoconjugados / Antineoplásicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Imunoconjugados / Antineoplásicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article