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Preliminary Structure-Activity Relationship Study of the MMV Pathogen Box Compound MMV675968 (2,4-Diaminoquinazoline) Unveils Novel Inhibitors of Trypanosoma brucei brucei.
Dize, Darline; Tata, Rolland Bantar; Keumoe, Rodrigue; Kouipou Toghueo, Rufin Marie; Tchatat, Mariscal Brice; Njanpa, Cyrille Ngansop; Tchuenguia, Vianey Claire; Yamthe, Lauve Tchokouaha; Fokou, Patrick Valere Tsouh; Laleu, Benoît; Duffy, James; Bishop, Ozlem Tastan; Boyom, Fabrice Fekam.
Afiliação
  • Dize D; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
  • Tata RB; Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6139, South Africa.
  • Keumoe R; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
  • Kouipou Toghueo RM; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
  • Tchatat MB; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
  • Njanpa CN; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
  • Tchuenguia VC; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
  • Yamthe LT; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
  • Fokou PVT; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
  • Laleu B; Medicines for Malaria Venture, Route de Pré-Bois 20, 1215 Meyrin, Switzerland.
  • Duffy J; Medicines for Malaria Venture, Route de Pré-Bois 20, 1215 Meyrin, Switzerland.
  • Bishop OT; Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6139, South Africa.
  • Boyom FF; Antimicrobial and Biocontrol Agents Unit (AmBcAU), Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.
Molecules ; 27(19)2022 Oct 04.
Article em En | MEDLINE | ID: mdl-36235118
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tripanossomicidas / Trypanosoma / Trypanosoma brucei brucei / Tripanossomíase Africana Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tripanossomicidas / Trypanosoma / Trypanosoma brucei brucei / Tripanossomíase Africana Idioma: En Ano de publicação: 2022 Tipo de documento: Article