Predictive model of persistent choledocholithiasis in patients with acute biliary pancreatitis.
Gastroenterol Hepatol
; 46(4): 297-304, 2023 Apr.
Article
em En, Es
| MEDLINE
| ID: mdl-36243251
ABSTRACT
BACKGROUND:
Choledocholithiasis causing acute biliary pancreatitis (ABP) may migrate to the duodenum or persist in the common bile duct (CBD). We developed a model for predicting persistent choledocholithiasis (PC) in patients with ABP.METHODS:
This retrospective cohort study included 204 patients, age ≥18 years (mean age 73 years, 65.7% women), admitted for ABP in 2013-2018, with at least a magnetic resonance cholangiopancreatography (MRCP), endoscopic ultrasonography (EUS), and/or endoscopic retrograde cholangiopancreatography (ERCP). Epidemiological, analytical, imaging, and endoscopic variables were compared between patients with and without PC. Multivariate logistic regression analyses were performed to develop a predictive model of PC.RESULTS:
Patients underwent MRCP (n=145, 71.1), MRCP and ERCP (n=44, 21.56%), EUS and ERCP (n=1, 0.49%), or ERCP (n=14, 6.86%). PC was detected in 49 patients (24%). PC was strongly associated with CBD dilation, detected in the emergency ultrasound (p<0.001; OR=27; 95% CI 5.8-185.5), increased blood levels of gamma glutamyl transpeptidase, detected at 72h (p=0.008; OR=3.4; 95% CI 1.5-8.9); and biliary sludge in the gallbladder (p=0.008; OR=0.03; 95% CI 0.001-0.3).CONCLUSIONS:
The predictive model showed a validated area under the curve (AUC) of 0.858 for detecting PC in patients with ABP. A nomogram was developed based on model results.CONCLUSIONS:
The predictive model was highly effective in detecting PC in patients with ABP. Therefore, this model could be useful in clinical practice.Palavras-chave
Acute biliary pancreatitis; Choledocolitiasis; Colangiografía por resonancia magnética; Colangiopancreatografía retrógrada endoscópica; Coledocolitiasis; Endoscopic retrograde cholangiopancreatography; Magnetic resonance imaging cholangiography; Modelo predictivo; Pancreatitis aguda biliar; Predictive model
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pancreatite
/
Coledocolitíase
Idioma:
En
/
Es
Ano de publicação:
2023
Tipo de documento:
Article