Assessing single-locus CRISPR/Cas9-based gene drive variants in the mosquito Aedes aegypti via single-generation crosses and modeling.

Reid, William; Williams, Adeline E; Sanchez-Vargas, Irma; Lin, Jingyi; Juncu, Rucsanda; Olson, Ken E; Franz, Alexander W E

Reid, William; Williams, Adeline E; Sanchez-Vargas, Irma; Lin, Jingyi; Juncu, Rucsanda; Olson, Ken E; Franz, Alexander W E.

Afiliação

Reid W; Department of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.
Williams AE; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Sanchez-Vargas I; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Lin J; Department of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.
Juncu R; Department of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.
Olson KE; Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Franz AWE; Department of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.

G3 (Bethesda) ; 12(12)2022 12 01.

Article em En | MEDLINE | ID: mdl-36250791

Assuntos

Aedes; Tecnologia de Impulso Genético; Infecção por Zika virus; Zika virus; Animais; Aedes/genética; Sistemas CRISPR-Cas/genética; Mosquitos Vetores/genética; Zika virus/genética; Infecção por Zika virus/genética

Palavras-chave

CRISPR; arbovirus; gene drive-blocking indels; genomic position effect; population replacement

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aedes / Zika virus / Infecção por Zika virus / Tecnologia de Impulso Genético Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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