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PD-L1-directed PlGF/VEGF blockade synergizes with chemotherapy by targeting CD141+ cancer-associated fibroblasts in pancreatic cancer.
Kim, Duk Ki; Jeong, Juhee; Lee, Dong Sun; Hyeon, Do Young; Park, Geon Woo; Jeon, Suwan; Lee, Kyung Bun; Jang, Jin-Young; Hwang, Daehee; Kim, Ho Min; Jung, Keehoon.
Afiliação
  • Kim DK; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.
  • Jeong J; Center for Biomolecular and Cellular Structure, Institute for Basic Science (IBS), Daejeon, 34126, Republic of Korea.
  • Lee DS; Department of Anatomy and Cell Biology, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
  • Hyeon DY; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, 03080, Republic of Korea.
  • Park GW; Department of Anatomy and Cell Biology, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
  • Jeon S; Center for Biomolecular and Cellular Structure, Institute for Basic Science (IBS), Daejeon, 34126, Republic of Korea.
  • Lee KB; School of Biological Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
  • Jang JY; Department of Anatomy and Cell Biology, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
  • Hwang D; Department of Anatomy and Cell Biology, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
  • Kim HM; Department of Pathology, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
  • Jung K; Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea.
Nat Commun ; 13(1): 6292, 2022 10 22.
Article em En | MEDLINE | ID: mdl-36272973

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Anticorpos de Cadeia Única / Fibroblastos Associados a Câncer / Antineoplásicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Anticorpos de Cadeia Única / Fibroblastos Associados a Câncer / Antineoplásicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article