The C-Terminus of the PSMA3 Proteasome Subunit Preferentially Traps Intrinsically Disordered Proteins for Degradation.

Biran, Assaf; Myers, Nadav; Steinberger, Shirel; Adler, Julia; Riutin, Marianna; Broennimann, Karin; Reuven, Nina; Shaul, Yosef

Biran, Assaf; Myers, Nadav; Steinberger, Shirel; Adler, Julia; Riutin, Marianna; Broennimann, Karin; Reuven, Nina; Shaul, Yosef.

Afiliação

Biran A; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Myers N; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Steinberger S; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Adler J; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Riutin M; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Broennimann K; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Reuven N; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.
Shaul Y; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

Cells ; 11(20)2022 10 14.

Article em En | MEDLINE | ID: mdl-36291102

Assuntos

Proteínas Intrinsicamente Desordenadas; Citoplasma/metabolismo; Proteínas Intrinsicamente Desordenadas/metabolismo; Poliubiquitina; Complexo de Endopeptidases do Proteassoma/metabolismo

Palavras-chave

20S proteasome; intrinsically disordered proteins; proteasomal degradation; proteostasis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Intrinsicamente Desordenadas Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Intrinsicamente Desordenadas Idioma: En Ano de publicação: 2022 Tipo de documento: Article