Increased mtDNA mutation frequency in oocytes causes epigenetic alterations and embryonic defects.

Han, Longsen; Chen, Yujia; Li, Ling; Ren, Chao; Wang, Haichao; Wu, Xinghan; Ge, Juan; Shu, Wenjie; Chen, Minjian; Wang, Qiang.

Afiliação

Han L; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Nanjing Medical University, Nanjing 211166, China.
Chen Y; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Nanjing Medical University, Nanjing 211166, China.
Li L; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Nanjing Medical University, Nanjing 211166, China.
Ren C; Department of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210033, China.
Wang H; Beijing Institute of Microbiology and Epidemiology, Beijing 100850, China.
Wu X; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Nanjing Medical University, Nanjing 211166, China.
Ge J; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Nanjing Medical University, Nanjing 211166, China.
Shu W; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Nanjing Medical University, Nanjing 211166, China.
Chen M; Beijing Institute of Microbiology and Epidemiology, Beijing 100850, China.
Wang Q; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Nanjing Medical University, Nanjing 211166, China.