Identification of the roasting reaction products of ferulic and sinapic acids and their xanthine oxidase inhibitory activity.

Shindo, Yukino; Taniguchi, Asuka; Masuda, Akiko; Masuda, Toshiya

Shindo, Yukino; Taniguchi, Asuka; Masuda, Akiko; Masuda, Toshiya.

Afiliação

Shindo Y; Graduate School of Human Life Science, Osaka Metropolitan University, Sumiyoshi, Osaka, Japan.
Taniguchi A; Graduate School of Human Life Science, Osaka Metropolitan University, Sumiyoshi, Osaka, Japan.
Masuda A; Graduate School of Human Life Science, Osaka Metropolitan University, Sumiyoshi, Osaka, Japan.
Masuda T; Graduate School of Human Life Science, Osaka Metropolitan University, Sumiyoshi, Osaka, Japan.

Biosci Biotechnol Biochem ; 87(1): 114-118, 2022 Dec 21.

Article em En | MEDLINE | ID: mdl-36328778

ABSTRACT

ABSTRACT

The roasting reaction products of ferulic and sinapic acids were analyzed using high-performance liquid chromatography (HPLC) and their constituent compounds were isolated. Structural analysis revealed that the major compounds were oligomers of the corresponding 4-vinylphenols. The xanthine oxidase (XO) inhibitory activity of the isolated compounds was also measured. Moderate XO inhibitory activity of some oligomers afforded from ferulic acid was observed.

Assuntos

Inibidores Enzimáticos; Xantina Oxidase; Inibidores Enzimáticos/farmacologia; Inibidores Enzimáticos/química; Cromatografia Líquida de Alta Pressão

Palavras-chave

ferulic acid; roasting reaction; sinapic acid; vinylphenol oligomer; xanthine oxidase inhibition

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Xantina Oxidase / Inibidores Enzimáticos Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Xantina Oxidase / Inibidores Enzimáticos Idioma: En Ano de publicação: 2022 Tipo de documento: Article