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Population-based discovery and Mendelian randomization analysis identify telmisartan as a candidate medicine for Alzheimer's disease in African Americans.
Zhang, Pengyue; Hou, Yuan; Tu, Wanzhu; Campbell, Noll; Pieper, Andrew A; Leverenz, James B; Gao, Sujuan; Cummings, Jeffrey; Cheng, Feixiong.
Afiliação
  • Zhang P; Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, Indiana, USA.
  • Hou Y; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
  • Tu W; Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, Indiana, USA.
  • Campbell N; Department of Pharmacy Practice, Purdue University, West Lafayette, Indiana, USA.
  • Pieper AA; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
  • Leverenz JB; Department of Psychiatry, Case Western Reserve University, Cleveland, Ohio, USA.
  • Gao S; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
  • Cummings J; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
  • Cheng F; Department of Neuroscience, Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA.
Alzheimers Dement ; 19(5): 1876-1887, 2023 05.
Article em En | MEDLINE | ID: mdl-36331056

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus / Doença de Alzheimer / Hipertensão Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diabetes Mellitus / Doença de Alzheimer / Hipertensão Idioma: En Ano de publicação: 2023 Tipo de documento: Article