Langerhans Cell Histiocytosis in a Pediatric Patient with Simultaneous Gastrointestinal and Skin Involvement: A Case Report and Literature Review.
Fetal Pediatr Pathol
; 42(3): 483-487, 2023 Jun.
Article
em En
| MEDLINE
| ID: mdl-36331524
ABSTRACT
Background:
Langerhans cell histiocytosis (LCH) has heterogeneous presentations involving single or multiple systems, but simultaneous isolated skin and gastrointestinal involvement is not common. Case report A female infant with intermittent bloody diarrhea was unresponsive for treatment of food allergy. Histology of gastric and colonic tissues demonstrated Langerhan's cell histiocytosis. The infant also had red rashes that were histologically proven Langerhan's cell histiocytosis. Chemotherapy utilized vincristine, cytarabine and prednisone. The bloody diarrhea and rash completely resolved with no recurrence in the 11 months of follow-up.Conclusion:
Langerhan cell histiocytosis may present with simultaneous gastrointestinal and skin involvement.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Histiocitose de Células de Langerhans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article