Significant impact of cachexia index on the outcomes after hepatic resection for colorectal liver metastases.
Ann Gastroenterol Surg
; 6(6): 804-812, 2022 Nov.
Article
em En
| MEDLINE
| ID: mdl-36338593
ABSTRACT
Introduction:
The purpose of this study was to investigate the relation between preoperative cachexia index (CXI) and long-term outcomes in patients with colorectal liver metastases (CRLM) after hepatic resection.Method:
In all,118 patients who underwent hepatic resection for CRLM were analyzed retrospectively. The relationship between CXI and the long-term outcomes in patients after hepatic resection was investigated. CXI was calculated based on preoperative skeletal muscle index, serum albumin level, and neutrophil-lymphocyte ratio.Results:
The multivariate analysis showed that extrahepatic lesion (hazard ratio [HR] 2.86, 95% confidence interval [CI] 1.48-5.53, P < .01) and high CXI (HR 0.44, 95% CI 0.20-0.98, P = .04) were independent and significant predictors of disease-free survival. Moreover, extrahepatic lesion (HR 2.32, 95% CI 1.03-5.22, P = .04), high CXI (HR 0.17, 95% CI 0.05-0.57, P < .01), and curability R 1 or 2 (HR 3.29, 95% CI 1.23-8.78, P = .02) were independent and significant predictors of overall survival.Conclusion:
CXI is a useful prognostic factor for disease-free survival and overall survival after hepatic resection in CRLM patients.
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MEDLINE
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Ano de publicação:
2022
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Article