New Boron Delivery Agents.
Cancer Biother Radiopharm
; 38(3): 160-172, 2023 Apr.
Article
em En
| MEDLINE
| ID: mdl-36350709
ABSTRACT
This proceeding article compiles current research on the development of boron delivery drugs for boron neutron capture therapy that was presented and discussed at the National Cancer Institute (NCI) Workshop on Neutron Capture Therapy that took place on April 20-22, 2022. The most used boron sources are icosahedral boron clusters attached to peptides, proteins (such as albumin), porphyrin derivatives, dendrimers, polymers, and nanoparticles, or encapsulated into liposomes. These boron clusters and/or carriers can be labeled with contrast agents allowing for the use of imaging techniques, such as PET, SPECT, and fluorescence, that enable quantification of tumor-localized boron and their use as theranostic agents.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Terapia por Captura de Nêutron de Boro
/
Neoplasias
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article