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Middle-Inner Macular Layers Dysfunction in a Case of Stellate Foveomacular Retinoschisis Detected by Abnormal Multifocal Photopic Negative Response Recordings.
Barbano, Lucilla; Antonelli, Giulio; Parravano, Mariacristina; Costanzo, Eliana; Parisi, Vincenzo; Ziccardi, Lucia.
Afiliação
  • Barbano L; IRCCS-Fondazione Bietti, Via Livenza 1, 00198 Rome, Italy.
  • Antonelli G; IRCCS-Fondazione Bietti, Via Livenza 1, 00198 Rome, Italy.
  • Parravano M; IRCCS-Fondazione Bietti, Via Livenza 1, 00198 Rome, Italy.
  • Costanzo E; IRCCS-Fondazione Bietti, Via Livenza 1, 00198 Rome, Italy.
  • Parisi V; IRCCS-Fondazione Bietti, Via Livenza 1, 00198 Rome, Italy.
  • Ziccardi L; IRCCS-Fondazione Bietti, Via Livenza 1, 00198 Rome, Italy.
Diagnostics (Basel) ; 12(11)2022 Nov 10.
Article em En | MEDLINE | ID: mdl-36359596
We describe the macular morpho-functional assessment of a 65-year-old man affected by stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR), studied by visual field, SD-OCT, autofluorescence, full-field electroretinogram (ffERG), multifocal electroretinogram (mfERG) and multifocal Photopic Negative Response (mfPhNR) recordings. The typical presentation consists of the foveal appearance of radial cartwheel pattern for the splitting of the retinal layers at the level of the Henle fiber layer (HFL) and the outer plexiform layer (OPL), perfectly seen by Spectral Domain-Optical Coherence Tomography (SD-OCT). Despite a normal function of the outer retina of the peripheral and central retina evaluated by ffERG and mfERG respectively, we observed a reduced function of the retinal elements involved in the retinoschisis by recording mfPhNR that assesses mainly inner retina function (retinal ganglion cells and their axons). Therefore, it is likely that the observed impaired mfPhNR responses reflect the signaling defects derived from the delaminated middle retina and transmitted to the innermost retinal layers.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article