A Primer on Chimerism Analysis: A Straightforward, Thorough Review.
Lab Med
; 54(4): 352-362, 2023 Jul 05.
Article
em En
| MEDLINE
| ID: mdl-36374737
ABSTRACT
Short tandem repeat (STR) analysis to assess chimerism is a critical aspect of routine care particularly in patients facing stem cell transplants but is also relevant in other clinical scenarios. STR analysis provides a means to assess donor and recipient cellular origins in a patient, and, as such, can inform engraftment, rejection, and relapse status in stem cell transplant recipients. In this review of STR testing, the most commonly used method to assess chimerism, its background, procedural details, and clinical utility are discussed.
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Base de dados:
MEDLINE
Assunto principal:
Transplante de Células-Tronco Hematopoéticas
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article