Knockout of ABC transporters by CRISPR/Cas9 contributes to reliable and accurate transporter substrate identification for drug discovery.

Feng, Dongyan; Zhong, Guorui; Zuo, Qingxia; Wan, Yanbin; Xu, Wanqing; He, Changsheng; Lin, Cailing; Huang, Dongchao; Chen, Feng; Huang, Lizhen.

Afiliação

Feng D; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Zhong G; Bioinformatics Institute, Agency for Science, Technology, and Research (ASTAR), Singapore, Singapore.
Zuo Q; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Wan Y; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Xu W; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
He C; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Lin C; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Huang D; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Chen F; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Huang L; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.