Development and validation of an LC-MS/MS method for the assessment of Isoxazole, a bioactive analogue of curcumin in rat plasma: Application to a pharmacokinetic study.

Nashik Sanap, Sachin; Sankar Bhatta, Rabi; Gupta, Nidhi; Gauttam, Vinod Kumar; Gupta, Sumeet

Nashik Sanap, Sachin; Sankar Bhatta, Rabi; Gupta, Nidhi; Gauttam, Vinod Kumar; Gupta, Sumeet.

Afiliação

Satyavert; Department of Pharmacology, M. M. College of Pharmacy, M. M. (Deemed to be University), Mullana, (Ambala), Haryana, India.
Nashik Sanap S; Pharmaceutics & Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow 226021, India.
Sankar Bhatta R; Pharmaceutics & Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow 226021, India.
Gupta N; Department of Pharmacecutical Chemistry, M. M. College of Pharmacy, M. M. (Deemed to be University), Mullana, (Ambala), Haryana, India.
Gauttam VK; Department of Pharmacy, IES University, Bhopal, Madhya Pardesh, India.
Gupta S; Department of Pharmacology, M. M. College of Pharmacy, M. M. (Deemed to be University), Mullana, (Ambala), Haryana, India. Electronic address: sumeetgupta25@mmumullana.org.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1212: 123488, 2022 Dec 01.

Article em En | MEDLINE | ID: mdl-36413908

Assuntos

Curcumina; Ratos; Animais; Cromatografia Líquida; Espectrometria de Massas em Tandem; Isoxazóis; Carbamazepina; Água

Palavras-chave

Bio-analytical method; Curcumin; Isoxazole; LC-MS/MS; Pharmacokinetics; Plasma; Validation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Curcumina Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Curcumina Idioma: En Ano de publicação: 2022 Tipo de documento: Article