Explore bioactive ingredients and potential mechanism of Houpo Mahuang decoction for chronic bronchitis based on UHPLC-Q exactive orbitrap HRMS, network pharmacology, and experiment verification.

Gao, Feng; Zhang, Tong; Zhang, Hao; Dai, Ziqi; Gu, Yuhao; Lu, Mingjun; Zhang, Zijie; Zeng, Qi; Shang, Bingxian; Gao, Shan; Wang, Nan; Xu, Bing; Lei, Haimin

Gao, Feng; Zhang, Tong; Zhang, Hao; Dai, Ziqi; Gu, Yuhao; Lu, Mingjun; Zhang, Zijie; Zeng, Qi; Shang, Bingxian; Gao, Shan; Wang, Nan; Xu, Bing; Lei, Haimin.

Afiliação

Gao F; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Zhang T; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Zhang H; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Dai Z; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Gu Y; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Lu M; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Zhang Z; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Zeng Q; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Shang B; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Gao S; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China.
Wang N; Aimin Pharmaceutical Group, Henan, 463500, China.
Xu B; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China. Electronic address: weichenxubing@126.com.
Lei H; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102400, China. Electronic address: hm_lei@126.com.

J Ethnopharmacol ; 303: 115924, 2023 Mar 01.

Article em En | MEDLINE | ID: mdl-36414217

Assuntos

Bronquite Crônica; Medicamentos de Ervas Chinesas; Animais; Camundongos; NF-kappa B; Cromatografia Líquida de Alta Pressão; Interleucina-6; Farmacologia em Rede; Fator de Necrose Tumoral alfa; Bronquite Crônica/tratamento farmacológico; Medicamentos de Ervas Chinesas/farmacologia; Medicamentos de Ervas Chinesas/uso terapêutico

Palavras-chave

Chronic bronchitis; Houpo Mahuang decoction; NF-κB signaling pathway; Network pharmacology; UHPLC-Q exactive orbitrap HRMS

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Bronquite Crônica Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Bronquite Crônica Idioma: En Ano de publicação: 2023 Tipo de documento: Article