Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report.

Falsaperla, Raffaele; Biondi, Giulia Marialidia; Motta, Milena; Gallerano, Pasquale; Tancredi, Giusi; Pavone, Piero; Ruggieri, Martino

Falsaperla, Raffaele; Biondi, Giulia Marialidia; Motta, Milena; Gallerano, Pasquale; Tancredi, Giusi; Pavone, Piero; Ruggieri, Martino.

Afiliação

Falsaperla R; Neonatal Intensive Care Unit, AUO Policlinico "Rodolico-San Marco", University of Catania, 95121 Catania, Italy.
Biondi GM; Postgraduate Training Program in Pediatrics, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Motta M; Neonatal Intensive Care Unit, AUO Policlinico "Rodolico-San Marco", University of Catania, 95121 Catania, Italy.
Gallerano P; Transfusional Medicine, Complex Operative Unit, PO "Giovanni Paolo II", 92019 Sciacca, Italy.
Tancredi G; Transfusional Medicine, Complex Operative Unit, PO "Giovanni Paolo II", 92019 Sciacca, Italy.
Pavone P; Section of Pediatrics and Child Neuropsichiatry, Department of Child and Experimental Medicine, University of Catania, AOU "Policlinico PO" G. Rodolico, 95123 Catania, Italy.
Ruggieri M; Unit of Rare Diseases of the Nervous System in Childhood, Department of Clinical and Experimental Medicine, Section of Pediatrics and Child Neuropsichiatry, University of Catania, AOU "Policlinico PO" G. Rodolico, 95123 Catania, Italy.

Children (Basel) ; 9(11)2022 Nov 17.

Article em En | MEDLINE | ID: mdl-36421216

ABSTRACT

ABSTRACT

BACKGROUND:

We evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation.

METHODS:

A CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in an experimental way, evaluating the efficacy described in the literature (selective bibliographic search in PubMed) of the use of blood products for non-transfusion purposes.

RESULTS:

A partial but satisfactory regeneration of the patient's nasal septum was observed. Using the free NIH Image J online software, we were able to calculate the regenerated surface (about 83% of the destroyed cartilage).