Activation of a Sweet Taste Receptor by Oleanane-Type Glycosides from Wisteria sinensis.
Molecules
; 27(22)2022 Nov 15.
Article
em En
| MEDLINE
| ID: mdl-36431968
ABSTRACT
The phytochemical study of Wisteria sinensis (Sims) DC. (Fabaceae), commonly known as the Chinese Wisteria, led to the isolation of seven oleanane-type glycosides from an aqueous-ethanolic extract of the roots. Among the seven isolated saponins, two have never been reported before 3-O-α-L-rhamnopyranosyl-(1â2)-ß-D-glucopyranosyl-(1â2)-ß-D-glucuronopyranosyl-22-O-acetylolean-12-ene-3ß,16ß,22ß,30-tetrol, and 3-O-ß-D-xylopyranosyl-(1â2)-ß-D-glucuronopyranosylwistariasapogenol A. Based on the close structures between the saponins from W. sinensis, and the glycyrrhizin from licorice, the stimulation of the sweet taste receptor TAS1R2/TAS1R3 by these glycosides was evaluated.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Saponinas
/
Wisteria
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article