Demonstration of continuous gradient elution functionality with automated liquid handling systems for high-throughput purification process development.

Rezvani, Kamiyar; Smith, Andrew; Javed, Jannat; Keller, William R; Stewart, Kevin D; Kim, Logan; Newell, Kelcy J

Rezvani, Kamiyar; Smith, Andrew; Javed, Jannat; Keller, William R; Stewart, Kevin D; Kim, Logan; Newell, Kelcy J.

Afiliação

Rezvani K; Purification Process Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, US.
Smith A; Robotics & Automation Development, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, US.
Javed J; Robotics & Automation Development, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, US.
Keller WR; Purification Process Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, US.
Stewart KD; Robotics & Automation Development, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, US.
Kim L; Purification Process Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, US.
Newell KJ; Robotics & Automation Development, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, US. Electronic address: kelcy.newell@astrazeneca.com.

J Chromatogr A ; 1687: 463658, 2023 Jan 04.

Article em En | MEDLINE | ID: mdl-36450201

Assuntos

Cromatografia; Confiabilidade dos Dados; Comércio

Palavras-chave

Chromatography; Gradient elution; High-throughput; Purification; Scale-down

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatografia / Confiabilidade dos Dados Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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XML

PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatografia / Confiabilidade dos Dados Idioma: En Ano de publicação: 2023 Tipo de documento: Article