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Patient-oriented risk score for predicting death 1 year after myocardial infarction: the SweDen risk score.
Rylance, Rebecca Tremain; Wagner, Philippe; Olesen, Kevin K W; Carlson, Jonas; Alfredsson, Joakim; Jernberg, Tomas; Leosdottir, Margret; Johansson, Pelle; Vasko, Peter; Maeng, Michael; Mohammed, Moman Aladdin; Erlinge, David.
Afiliação
  • Rylance RT; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden rebecca.rylance@med.lu.se.
  • Wagner P; Center for Clinical Research, Uppsala University, Uppsala, Sweden.
  • Olesen KKW; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
  • Carlson J; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.
  • Alfredsson J; Department of Cardiology, Karolinska University Hospital, Linkoping, Sweden.
  • Jernberg T; The Swedish Heart and Lung Association, Stockholm, Sweden.
  • Leosdottir M; Department of Clinical Sciences, Skåne University Hospital Lund, Malmö, Sweden.
  • Johansson P; Department of Clinical Sciences, Lund University, Malmo, Sweden.
  • Vasko P; The Swedish Heart Failure Registry, Stockholm, Sweden.
  • Maeng M; Department of Cardiology, Karolinska University Hospital, Linkoping, Sweden.
  • Mohammed MA; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.
  • Erlinge D; Department of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.
Open Heart ; 9(2)2022 12.
Article em En | MEDLINE | ID: mdl-36460308
OBJECTIVES: Our aim was to derive, based on the SWEDEHEART registry, and validate, using the Western Denmark Heart registry, a patient-oriented risk score, the SweDen score, which could calculate the risk of 1-year mortality following a myocardial infarction (MI). METHODS: The factors included in the SweDen score were age, sex, smoking, diabetes, heart failure and statin use. These were chosen a priori by the SWEDEHEART steering group based on the premise that the factors were information known by the patients themselves. The score was evaluated using various statistical methods such as time-dependent receiver operating characteristics curves of the linear predictor, area under the curve metrics, Kaplan-Meier survivor curves and the calibration slope. RESULTS: The area under the curve values were 0.81 in the derivation data and 0.76 in the validation data. The Kaplan-Meier curves showed similar patient profiles across datasets. The calibration slope was 1.03 (95% CI 0.99 to 1.08) in the validation data using the linear predictor from the derivation data. CONCLUSIONS: The SweDen risk score is a novel tool created for patient use. The risk score calculator will be available online and presents mortality risk on a colour scale to simplify interpretation and to avoid exact life span expectancies. It provides a validated patient-oriented risk score predicting the risk of death within 1 year after suffering an MI, which visualises the benefit of statin use and smoking cessation in a simple way.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Hidroximetilglutaril-CoA Redutases / Insuficiência Cardíaca / Infarto do Miocárdio Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Hidroximetilglutaril-CoA Redutases / Insuficiência Cardíaca / Infarto do Miocárdio Idioma: En Ano de publicação: 2022 Tipo de documento: Article