Carrier-free Chinese herbal small molecules self-assembly with 3D-porous crystal framework as a synergistic anti-AD agent.

Shen, Rui; Chen, Yuhong; Li, Xiangyu; Wang, Xi; Yang, Aihong; Kou, Xiaodi

Shen, Rui; Chen, Yuhong; Li, Xiangyu; Wang, Xi; Yang, Aihong; Kou, Xiaodi.

Afiliação

Shen R; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Chen Y; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Li X; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Wang X; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Yang A; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. Electronic address: yah408@163.com.
Kou X; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China. Electronic address: xiaodikou2013@163.com.

Int J Pharm ; 630: 122458, 2023 Jan 05.

Article em En | MEDLINE | ID: mdl-36462740

Assuntos

Doença de Alzheimer; Berberina; Medicamentos de Ervas Chinesas; Doenças Neurodegenerativas; Animais; Humanos; Doença de Alzheimer/tratamento farmacológico; Berberina/química; Caenorhabditis elegans; Medicamentos de Ervas Chinesas/química; Porosidade; Espécies Reativas de Oxigênio; Rizoma

Palavras-chave

3D-porous frame crystal structure; Carrier-free; Chinese herbal small molecules; Self-assembly; Synergistic anti-AD efficacy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Berberina / Medicamentos de Ervas Chinesas / Doenças Neurodegenerativas / Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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