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Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression.
Trzaskalski, Natasha A; Vulesevic, Branka; Nguyen, My-Anh; Jeraj, Natasha; Fadzeyeva, Evgenia; Morrow, Nadya M; Locatelli, Cassandra Aa; Travis, Nicole; Hanson, Antonio A; Nunes, Julia Rc; O'Dwyer, Conor; van der Veen, Jelske N; Lorenzen-Schmidt, Ilka; Seymour, Rick; Pulente, Serena M; Clément, Andrew C; Crawley, Angela M; Jacobs, René L; Doyle, Mary-Anne; Cooper, Curtis L; Kim, Kyoung-Han; Fullerton, Morgan D; Mulvihill, Erin E.
Afiliação
  • Trzaskalski NA; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Vulesevic B; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • Nguyen MA; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Jeraj N; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • Fadzeyeva E; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Morrow NM; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • Locatelli CA; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Travis N; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • Hanson AA; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Nunes JR; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • O'Dwyer C; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • van der Veen JN; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • Lorenzen-Schmidt I; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Seymour R; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • Pulente SM; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Clément AC; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • Crawley AM; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Jacobs RL; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • Doyle MA; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Cooper CL; Centre for Infection, Immunity and Inflammation, Ottawa, Ontario, Canada.
  • Kim KH; Centre for Catalysis Research and Innovation, Ottawa, Ontario, Canada.
  • Fullerton MD; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
  • Mulvihill EE; Centre for Infection, Immunity and Inflammation, Ottawa, Ontario, Canada.
JCI Insight ; 8(2)2023 Jan 24.
Article em En | MEDLINE | ID: mdl-36472923
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatite C / Hepatopatia Gordurosa não Alcoólica Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatite C / Hepatopatia Gordurosa não Alcoólica Idioma: En Ano de publicação: 2023 Tipo de documento: Article