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Longitudinal Virological and Immunological Profile in a Case of Human Monkeypox Infection.
Zingaropoli, Maria Antonella; Parente, Alberico; Kertusha, Blerta; Campagna, Roberta; Tieghi, Tiziana; Garattini, Silvia; Marocco, Raffaella; Carraro, Anna; Tortellini, Eeva; Guardiani, Mariasilvia; Dominelli, Federica; Turriziani, Ombretta; Ciardi, Maria Rosa; Mastroianni, Claudio Maria; Del Borgo, Cosmo; Lichtner, Miriam.
Afiliação
  • Zingaropoli MA; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Parente A; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Kertusha B; Infectious Diseases Unit, SM Goretti Hospital, Sapienza University of Rome, Latina, Italy.
  • Campagna R; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
  • Tieghi T; Infectious Diseases Unit, SM Goretti Hospital, Sapienza University of Rome, Latina, Italy.
  • Garattini S; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Marocco R; Infectious Diseases Unit, SM Goretti Hospital, Sapienza University of Rome, Latina, Italy.
  • Carraro A; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Tortellini E; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Guardiani M; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Dominelli F; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Turriziani O; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
  • Ciardi MR; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Mastroianni CM; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
  • Del Borgo C; Infectious Diseases Unit, SM Goretti Hospital, Sapienza University of Rome, Latina, Italy.
  • Lichtner M; Infectious Diseases Unit, SM Goretti Hospital, Sapienza University of Rome, Latina, Italy.
Open Forum Infect Dis ; 9(12): ofac569, 2022 Dec.
Article em En | MEDLINE | ID: mdl-36474633
ABSTRACT
In a male with severe proctitis, monkeypox virus DNA was detected in skin lesions, blood, the nasopharynx, and the rectum, underlying generalized viral spreading. Rectal involvement was still found when skin lesions disappeared. At this early stage, an increase of cytotoxic and activated T cells was observed, while a reduction in CD56dimCD57+ NK cells compared with recovery time point was observed.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article