AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope.

Wainstein, Ehud; Maik-Rachline, Galia; Blenis, John; Seger, Rony

Wainstein, Ehud; Maik-Rachline, Galia; Blenis, John; Seger, Rony.

Afiliação

Wainstein E; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.
Maik-Rachline G; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.
Blenis J; Meyer Cancer Center and Department of Pharmacology, Weill Cornell Medical College, New York, NY 10021, USA.
Seger R; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: rony.seger@weizmann.ac.il.

Cell Rep ; 41(10): 111733, 2022 12 06.

Article em En | MEDLINE | ID: mdl-36476861

Assuntos

Membrana Nuclear; Proteínas Proto-Oncogênicas c-akt; Humanos

Palavras-chave

AKT; CP: Cell biology; Tsc2; nuclear envelope; phosphorylation; subcellular localization

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-akt / Membrana Nuclear Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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