High PPFIA1 expression promotes cancer survival by suppressing CD8+ T cells in breast cancer: drug discovery and machine learning approach.

Chu, Jinah; Min, Kyueng-Whan; Kim, Dong-Hoon; Son, Byoung Kwan; Kim, Hyung Suk; Jung, Un Suk; Kwon, Mi Jung; Do, Sung-Im

Chu, Jinah; Min, Kyueng-Whan; Kim, Dong-Hoon; Son, Byoung Kwan; Kim, Hyung Suk; Jung, Un Suk; Kwon, Mi Jung; Do, Sung-Im.

Afiliação

Chu J; Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunanro, Jongno-gu, Seoul, Republic of Korea.
Min KW; Department of Pathology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Gyeonggi-do, Republic of Korea. kyueng@hanyang.ac.kr.
Kim DH; Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunanro, Jongno-gu, Seoul, Republic of Korea. idavid.kim@samsung.com.
Son BK; Department of Internal Medicine, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Gyeonggi-do, Republic of Korea.
Kim HS; Division of Breast Surgery, Department of Surgery, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Gyeonggi-do, Republic of Korea.
Jung US; Department of Obstetrics and Gynecology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Gyeonggi-do, Republic of Korea.
Kwon MJ; Department of Pathology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Gyeonggi-do, Republic of Korea.
Do SI; Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunanro, Jongno-gu, Seoul, Republic of Korea.

Breast Cancer ; 30(2): 259-270, 2023 Mar.

Article em En | MEDLINE | ID: mdl-36478321

Assuntos

Neoplasias da Mama; Humanos; Feminino; Neoplasias da Mama/patologia; Cloridrato de Erlotinib; Proteínas Adaptadoras de Transdução de Sinal/genética; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Prognóstico; Antígeno B7-H1/metabolismo; Linfócitos T CD8-Positivos/metabolismo; Descoberta de Drogas; Linfócitos T/patologia; Linfócitos do Interstício Tumoral

Palavras-chave

Breast cancer; Drug; Machine learning; PPFIA1; Prognosis; Tumor-infiltrating lymphocytes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Idioma: En Ano de publicação: 2023 Tipo de documento: Article