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Streptogramin A derivatives as mitochondrial translation inhibitors to suppress glioblastoma stem cell growth.
Sighel, Denise; Battistini, Giulia; Rosatti, Emanuele Filiberto; Vigna, Jacopo; Pavan, Matteo; Belli, Romina; Peroni, Daniele; Alessandrini, Federica; Longhi, Sara; Pancher, Michael; Rorbach, Joanna; Moro, Stefano; Quattrone, Alessandro; Mancini, Ines.
Afiliação
  • Sighel D; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123, Povo, Trento, Italy. Electronic address: denise.sighel@unitn.it.
  • Battistini G; Laboratory of Bioorganic Chemistry, Department of Physics, University of Trento, Via Sommarive 14, 38123, Povo, Trento, Italy.
  • Rosatti EF; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123, Povo, Trento, Italy.
  • Vigna J; Laboratory of Bioorganic Chemistry, Department of Physics, University of Trento, Via Sommarive 14, 38123, Povo, Trento, Italy.
  • Pavan M; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via F. Marzolo 5, 35131, Padova, Italy.
  • Belli R; Mass Spectrometry and Proteomics Core Facility, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123, Povo, Trento, Italy.
  • Peroni D; Mass Spectrometry and Proteomics Core Facility, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123, Povo, Trento, Italy.
  • Alessandrini F; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123, Povo, Trento, Italy.
  • Longhi S; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123, Povo, Trento, Italy.
  • Pancher M; High Throughput Screening (HTS) and Validation Core Facility, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123, Povo, Trento, Italy.
  • Rorbach J; Department of Medical Biochemistry and Biophysics, Division of Molecular Metabolism, Biomedicum, Solnavägen 9, 171 65, Solna, Stockholm, Sweden.
  • Moro S; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via F. Marzolo 5, 35131, Padova, Italy.
  • Quattrone A; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, 38123, Povo, Trento, Italy.
  • Mancini I; Laboratory of Bioorganic Chemistry, Department of Physics, University of Trento, Via Sommarive 14, 38123, Povo, Trento, Italy. Electronic address: ines.mancini@unitn.it.
Eur J Med Chem ; 246: 114979, 2023 Jan 15.
Article em En | MEDLINE | ID: mdl-36495628
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glioblastoma / Estreptograminas Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glioblastoma / Estreptograminas Idioma: En Ano de publicação: 2023 Tipo de documento: Article