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Steroidal alkaloid with unprecedented triheterocyclic architecture.
Zhou, Zhong-Shun; Zhao, Yun-Li; Hu, Bin-Yuan; Wang, Bei; Liu, Ya-Ping; Zhu, Yan-Yan; He, Ying-Jie; Wang, Zhao-Jie; Dai, Zhi; Zhao, Li-Xing; Luo, Xiao-Dong.
Afiliação
  • Zhou ZS; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China. xdluo@ynu.edu.cn.
  • Zhao YL; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China. xdluo@ynu.edu.cn.
  • Hu BY; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China. xdluo@ynu.edu.cn.
  • Wang B; Key Laboratory of Herbal-Tebitan Drug Screening and Deep Processing of Gansu Province, School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, P. R. China.
  • Liu YP; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, P. R. China.
  • Zhu YY; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China. xdluo@ynu.edu.cn.
  • He YJ; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China. xdluo@ynu.edu.cn.
  • Wang ZJ; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China. xdluo@ynu.edu.cn.
  • Dai Z; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China. xdluo@ynu.edu.cn.
  • Zhao LX; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China. xdluo@ynu.edu.cn.
  • Luo XD; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, Yunnan Characteristic Plant Extraction Laboratory, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China. xdluo@ynu.edu.cn.
Chem Commun (Camb) ; 59(3): 326-329, 2023 Jan 03.
Article em En | MEDLINE | ID: mdl-36511292
ABSTRACT
Veratrazine A (1), a steroidal alkaloid with a unique 6/5/5 triheterocyclic scaffold as the side chain, was isolated from Veratrum stenophyllum, and its structure was established via spectroscopic analyses and X-ray diffraction. A plausible biosynthetic pathway for 1 is proposed. Bioassy exhibits moderate anti-inflammatory activities in vitro and in vivo.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Veratrum / Alcaloides / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Veratrum / Alcaloides / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article