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The use of the sodium fluorescein and YELLOW 560 nm filter for the resection of pediatric posterior fossa lesions.
Ott, Christian; Proescholdt, Martin; Friedrich, Monika; Hoehne, Julius; Rosengarth, Katharina; Schmidt, Nils-Ole; Schebesch, Karl-Michael.
Afiliação
  • Ott C; Department of Neurosurgery, University Hospital Regensburg, Regensburg, Germany. christian.ott@ukr.de.
  • Proescholdt M; Department of Neurosurgery, University Hospital Regensburg, Regensburg, Germany.
  • Friedrich M; Department of Neurosurgery, University Hospital Regensburg, Regensburg, Germany.
  • Hoehne J; Department of Neurosurgery, University Hospital Regensburg, Regensburg, Germany.
  • Rosengarth K; Department of Neurosurgery, University Hospital Regensburg, Regensburg, Germany.
  • Schmidt NO; Department of Neurosurgery, University Hospital Regensburg, Regensburg, Germany.
  • Schebesch KM; Department of Neurosurgery, University Hospital Regensburg, Regensburg, Germany.
Childs Nerv Syst ; 39(6): 1495-1500, 2023 06.
Article em En | MEDLINE | ID: mdl-36527464
ABSTRACT

PURPOSE:

This study aimed to verify the feasibility, safety, and benefit of using fluorescein sodium (FL) and a YELLOW 560 nm filter in posterior fossa tumors in children.

METHODS:

All cases of pediatric posterior fossa tumors that have undergone surgery using fluorescein (2018-2022) have been included and were examined retrospectively. In those cases where resection of the tumor was planned, a blinded neuroradiologist distinguished gross total resection and subtotal resection according to the postoperative MRI findings. The surgical report and medical files were reviewed regarding the intraoperative staining grade and adverse events. The grade of fluorescent staining of the targeted lesion was assessed as described in the surgical reports. The screening was conducted for any reference to the degree of fluorescent staining "intense," "medium," "slight," and "no staining."

RESULTS:

19 cases have been included. In 14 cases, a complete resection was initially intended. In 11 of these cases, a gross total resection could be achieved (78.6%). Staining was described as intense in most cases (58.8%). Except for yellow-colored urine, no side effects obviously related to FL were found throughout the observation period.

CONCLUSION:

In combination with a specific filter, FL is a reliable, safe, and feasible tool in posterior fossa surgery in children.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Neoplasias Infratentoriais Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Neoplasias Infratentoriais Idioma: En Ano de publicação: 2023 Tipo de documento: Article