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Autologous bone marrow-derived MSCs engineered to express oFVIII-FLAG engraft in adult sheep and produce an effective increase in plasma FVIII levels.
Trevisan, Brady; Rodriguez, Martin; Medder, Hailey; Lankford, Shannon; Combs, Rebecca; Owen, John; Atala, Anthony; Porada, Christopher D; Almeida-Porada, Graça.
Afiliação
  • Trevisan B; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine, Winston-Salem, NC, United States.
  • Rodriguez M; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine, Winston-Salem, NC, United States.
  • Medder H; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine, Winston-Salem, NC, United States.
  • Lankford S; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine, Winston-Salem, NC, United States.
  • Combs R; Special Hematology Laboratory, Wake Forest School of Medicine, Winston-Salem, NC, United States.
  • Owen J; Special Hematology Laboratory, Wake Forest School of Medicine, Winston-Salem, NC, United States.
  • Atala A; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine, Winston-Salem, NC, United States.
  • Porada CD; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine, Winston-Salem, NC, United States.
  • Almeida-Porada G; Wake Forest Institute for Regenerative Medicine, Fetal Research and Therapy Program, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Front Immunol ; 13: 1070476, 2022.
Article em En | MEDLINE | ID: mdl-36532079
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Mesenquimais / Hemofilia A Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Mesenquimais / Hemofilia A Idioma: En Ano de publicação: 2022 Tipo de documento: Article