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Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo.
Bachmann, Magdalena; Rossa, Andrea; Varanita, Tatiana; Fioretti, Bernard; Biasutto, Lucia; Milenkovic, Stefan; Checchetto, Vanessa; Peruzzo, Roberta; Ahmad, Syed A; Patel, Sameer H; Lukowski, Robert; Edwards, Michael J; Ceccarelli, Matteo; Gulbins, Erich; Zoratti, Mario; Mattarei, Andrea; Szabo, Ildiko.
Afiliação
  • Bachmann M; Department of Biology, University of Padova, Padova, Italy. magdalena.bachmann@unipd.it.
  • Rossa A; Department of Chemical Sciences, University of Padova, Padova, Italy.
  • Varanita T; Department of Biology, University of Padova, Padova, Italy.
  • Fioretti B; Department of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Italy.
  • Biasutto L; CNR Institute of Neuroscience, Padova, Italy.
  • Milenkovic S; CNR Institute of Materials, Cagliari, Italy.
  • Checchetto V; Department of Biology, University of Padova, Padova, Italy.
  • Peruzzo R; Department of Biology, University of Padova, Padova, Italy.
  • Ahmad SA; Department of Surgery, University of Cincinnati, Cincinnati, USA.
  • Patel SH; Department of Surgery, University of Cincinnati, Cincinnati, USA.
  • Lukowski R; Department of Pharmacology, Toxicology and Clinical Pharmacy, University of Tübingen, Tübingen, Germany.
  • Edwards MJ; Department of Surgery, University of Cincinnati, Cincinnati, USA.
  • Ceccarelli M; CNR Institute of Materials, Cagliari, Italy.
  • Gulbins E; Department of Physics, University of Cagliari, Monserrato, Italy.
  • Zoratti M; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany.
  • Mattarei A; CNR Institute of Neuroscience, Padova, Italy.
  • Szabo I; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. andrea.mattarei@unipd.it.
Cell Death Dis ; 13(12): 1055, 2022 12 20.
Article em En | MEDLINE | ID: mdl-36539400
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Canais de Potássio Cálcio-Ativados / Melanoma Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Canais de Potássio Cálcio-Ativados / Melanoma Idioma: En Ano de publicação: 2022 Tipo de documento: Article