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Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida.
Simar, Shelby R; Tran, Truc T; Rydell, Kirsten B; Panesso, Diana; Contreras, German A; Munita, Jose M; Cifuentes, Renzo O; Abbo, Lilian M; Sahasrabhojane, Pranoti; Dinh, An Q; Axell-House, Dierdre B; Savidge, Tor; Shelburne, Samuel A; Hanson, Blake M; Arias, Cesar A.
Afiliação
  • Simar SR; Center for Infectious Diseases, University of Texas Health Science Center, School of Public Health, Houston, Texas, USA.
  • Tran TT; Division of Infectious Diseases, Houston Methodist Hospital, Houston, Texas, USA.
  • Rydell KB; Center for Infectious Diseases, Houston Methodist Research Institute, Houston, Texas, USA.
  • Panesso D; Division of Infectious Diseases, Houston Methodist Hospital, Houston, Texas, USA.
  • Contreras GA; Center for Infectious Diseases, Houston Methodist Research Institute, Houston, Texas, USA.
  • Munita JM; Division of Infectious Diseases, Houston Methodist Hospital, Houston, Texas, USA.
  • Cifuentes RO; Center for Infectious Diseases, Houston Methodist Research Institute, Houston, Texas, USA.
  • Abbo LM; Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, Bogotá, Colombia.
  • Sahasrabhojane P; Division of Infectious Diseases, Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center, Houston, Texas, USA.
  • Dinh AQ; Genomics and Resistant Microbes (GeRM) Group, Facultad de Medicina Clínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.
  • Axell-House DB; Millennium Initiative for Collaborative Research On Bacterial Resistance (MICROB-R), Santiago, Chile.
  • Savidge T; Jackson Health System, Miami Transplant Institute, Miami, Florida, USA.
  • Shelburne SA; Jackson Health System, Miami Transplant Institute, Miami, Florida, USA.
  • Hanson BM; Department of Infectious Diseases, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Arias CA; Division of Infectious Diseases, Houston Methodist Hospital, Houston, Texas, USA.
Antimicrob Agents Chemother ; 67(1): e0128422, 2023 01 24.
Article em En | MEDLINE | ID: mdl-36541772
ABSTRACT
In the United States, vanB-mediated resistance in enterococci is rare. We characterized three sequence type (ST) 6, vancomycin-resistant Enterococcus faecalis isolates causing bacteremia in unique patients in spatiotemporally distinct settings. Isolates were recovered between 2018 and 2020 in two cities in the United States (Houston, TX; Miami, FL). The isolates harbored the vanB operon on a chromosomally located Tn1549 transposon, and epidemiological data suggested multiple introductions of the vanB gene cluster into ST6 E. faecalis.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Bactérias Gram-Positivas / Enterococcus faecium / Enterococos Resistentes à Vancomicina Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Bactérias Gram-Positivas / Enterococcus faecium / Enterococos Resistentes à Vancomicina Idioma: En Ano de publicação: 2023 Tipo de documento: Article