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CeO2-Azacrown Conjugate as a Nanoplatform for Combined Radiopharmaceuticals.
Khabirova, Sofia; Aleshin, Gleb; Plakhova, Tatiana; Zubenko, Anastasia; Shchukina, Anna; Fedorova, Olga; Averin, Aleksey; Belova, Ekaterina; Bazarkina, Elena; Kvashnina, Kristina; Kalmykov, Stepan.
Afiliação
  • Khabirova S; Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory, 1/3, 119991 Moscow, Russia.
  • Aleshin G; Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory, 1/3, 119991 Moscow, Russia.
  • Plakhova T; Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory, 1/3, 119991 Moscow, Russia.
  • Zubenko A; N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Vavilova, 28, GSP-1, 119991 Moscow, Russia.
  • Shchukina A; N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Vavilova, 28, GSP-1, 119991 Moscow, Russia.
  • Fedorova O; N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Vavilova, 28, GSP-1, 119991 Moscow, Russia.
  • Averin A; Frumkin Institute of Physical Chemistry and Electrochemistry Russian Academy of Sciences, Leninskiy Ave. 31b4, 119991 Moscow, Russia.
  • Belova E; Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory, 1/3, 119991 Moscow, Russia.
  • Bazarkina E; The Rossendorf Beamline at ESRF-The European Synchrotron, CS40220, CEDEX 9, 38043 Grenoble, France.
  • Kvashnina K; Helmholtz Zentrum Dresden-Rossendorf (HZDR), Institute of Resource Ecology, P.O. Box 510119, 01314 Dresden, Germany.
  • Kalmykov S; The Rossendorf Beamline at ESRF-The European Synchrotron, CS40220, CEDEX 9, 38043 Grenoble, France.
Nanomaterials (Basel) ; 12(24)2022 Dec 18.
Article em En | MEDLINE | ID: mdl-36558337
This study is one of the first attempts to assess CeO2 nanoparticles as a nanoplatform for radiopharmaceuticals with radionuclides. The process of functionalization using a bifunctional azacrown ligand is described, and the resulting conjugates are characterized by IR and Raman spectroscopy. Their complexes with 207Bi show a high stability in medically relevant media, thus encouraging the further study of these conjugates in vivo as potential combined radiopharmaceuticals.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article