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Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinoma.
Raninga, Prahlad V; He, Yaowu; Datta, Keshava K; Lu, Xue; Maheshwari, Uma R; Venkat, Pooja; Mayoh, Chelsea; Gowda, Harsha; Kalimutho, Murugan; Hooper, John D; Khanna, Kum Kum.
Afiliação
  • Raninga PV; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD 4006, Australia. Electronic address: prahlad.raninga@qimrberghofer.edu.au.
  • He Y; Mater Research Institute, The University of Queensland, Translational Research Institute, Woolloongabba, QLD 4102, Australia.
  • Datta KK; Proteomics and Metabolomics Platform, La Trobe University, Melbourne, VIC 3086, Australia.
  • Lu X; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD 4006, Australia.
  • Maheshwari UR; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD 4006, Australia.
  • Venkat P; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW 2750, Australia.
  • Mayoh C; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW 2750, Australia.
  • Gowda H; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD 4006, Australia.
  • Kalimutho M; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD 4006, Australia.
  • Hooper JD; Mater Research Institute, The University of Queensland, Translational Research Institute, Woolloongabba, QLD 4102, Australia.
  • Khanna KK; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Brisbane, QLD 4006, Australia. Electronic address: kumkum.khanna@qimrberghofer.edu.au.
Mol Ther ; 31(3): 729-743, 2023 03 01.
Article em En | MEDLINE | ID: mdl-36560881
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Tiorredoxina Dissulfeto Redutase / Genes myc / Auranofina / Glutamina Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Tiorredoxina Dissulfeto Redutase / Genes myc / Auranofina / Glutamina Idioma: En Ano de publicação: 2023 Tipo de documento: Article