Vitamin D3 and Lactobacillus rhamnosus GG/p40 Synergize to Protect Mice From Colitis by Promoting Vitamin D Receptor Expression and Epithelial Proliferation.

Chen, Dan; Tang, Hao; Li, Yue; Yang, Hong; Wang, Hongying; Tan, Bei; Qian, Jiaming

Chen, Dan; Tang, Hao; Li, Yue; Yang, Hong; Wang, Hongying; Tan, Bei; Qian, Jiaming.

Afiliação

Chen D; Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Tang H; Department of Gastroenterology, Beijing Hospital, National Center of Gerontology Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Li Y; Department of Internal Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Chinaand.
Yang H; Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wang H; Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Tan B; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qian J; Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Inflamm Bowel Dis ; 29(4): 620-632, 2023 04 03.

Article em En | MEDLINE | ID: mdl-36562589

There is increasing evidence that vitamin D and its associated pathways may be a helpful adjunct to inflammatory bowel disease therapies. This experimental study shows that vitamin D may synergize with the probiotic Lactobacillus rhamnosus GG for enhanced therapeutic effect.

Assuntos

Colite; Doenças Inflamatórias Intestinais; Lacticaseibacillus rhamnosus; Animais; Camundongos; Receptores de Calcitriol/genética; Colecalciferol; Colite/induzido quimicamente; Colite/prevenção & controle; Colite/metabolismo; Colo/patologia; Doenças Inflamatórias Intestinais/patologia; Proliferação de Células; Sulfato de Dextrana/toxicidade; Camundongos Endogâmicos C57BL; Modelos Animais de Doenças

Palavras-chave

Lactobacillus rhamnoides GG; colitis; p40; vitamin D; vitamin D receptor

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Colite / Lacticaseibacillus rhamnosus Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google