Fetal and neonatal alloimmune thrombocytopenia: Current pathophysiological insights and perspectives for future diagnostics and treatment.

Stam, Wendy; Wachholz, Gabriela Elis; de Pereda, Jose Maria; Kapur, Rick; van der Schoot, Ellen; Margadant, Coert

Stam, Wendy; Wachholz, Gabriela Elis; de Pereda, Jose Maria; Kapur, Rick; van der Schoot, Ellen; Margadant, Coert.

Afiliação

Stam W; Institute of Biology, Leiden University, Leiden, the Netherlands; Cancer Center Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands. Electronic address: w.stam1@amsterdamumc.nl.
Wachholz GE; Cancer Center Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands. Electronic address: g.e.wachholz@amsterdamumc.nl.
de Pereda JM; Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Salamanca, 37007 Salamanca, Spain. Electronic address: pereda@usal.es.
Kapur R; Sanquin Research, Department of Experimental Immunohematology, Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: R.Kapur@sanquin.nl.
van der Schoot E; Sanquin Research, Department of Experimental Immunohematology, Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: e.vanderschoot@sanquin.nl.
Margadant C; Institute of Biology, Leiden University, Leiden, the Netherlands; Cancer Center Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands. Electronic address: c.margadant@amsterdamumc.nl.

Blood Rev ; 59: 101038, 2023 05.

Article em En | MEDLINE | ID: mdl-36581513

Assuntos

Trombocitopenia Neonatal Aloimune; Animais; Camundongos; Gravidez; Feminino; Humanos; Trombocitopenia Neonatal Aloimune/diagnóstico; Trombocitopenia Neonatal Aloimune/etiologia; Trombocitopenia Neonatal Aloimune/terapia; Placenta/metabolismo; Células Endoteliais; Plaquetas/metabolismo; Isoanticorpos

Palavras-chave

Alloimmune response; Angiogenesis; Development; HPA-1a; Hemorrhage; Human platelet antigen incompatibility; Immunohematology; Integrin; Pregnancy; Thrombocytopenia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombocitopenia Neonatal Aloimune Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombocitopenia Neonatal Aloimune Idioma: En Ano de publicação: 2023 Tipo de documento: Article