Multiple pneumatoceles and lung abscesses caused by early-onset E. coli sepsis in a preterm neonate.
J Infect Chemother
; 29(4): 414-417, 2023 Apr.
Article
em En
| MEDLINE
| ID: mdl-36584814
ABSTRACT
Early-onset sepsis (EOS) is a serious and fatal illness in neonates, Group B Streptococcus and Escherichia coli are major causative pathogens. We report a case of EOS and pneumonia caused by E. coli in a preterm neonate with multiple pneumatoceles and lung abscesses. A male neonate weighing 1670g was delivered at 33 6/7 weeks' gestation by a mother with clinical chorioamnionitis. He showed respiratory distress soon after birth and developed septic shock. He was intubated and mechanical ventilation was started. E.coli was detected in blood culture obtained from both the patient and his mother. He developed multiple pneumatoceles and lung abscesses. Surgical drainage was complicated, cefotaxime was thus continued until day 74. Pneumatoceles and lung abscesses are complications of neonatal pneumonia, rarely reported by E. coli. Multiple lung abscesses in our patient are distinct from single abscesses in previous case studies of neonatal lung abscesses. We speculate that bacteremia along with pneumatoceles led to multiple lung abscesses in our patient. These complications require long-term antibiotic therapy, to minimize morbidity and mortality, and should thus be considered when managing EOS caused by E. coli.
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Base de dados:
MEDLINE
Assunto principal:
Pneumonia
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Bacteriemia
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Sepse
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Cistos
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Infecções por Escherichia coli
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Sepse Neonatal
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Abscesso Pulmonar
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article