The impact of preoperative total parenteral nutrition on the surgical complications of Crohn's disease: A retrospective cohort study.
Saudi J Gastroenterol
; 29(3): 158-163, 2023.
Article
em En
| MEDLINE
| ID: mdl-36588367
ABSTRACT
Background:
Crohn's disease (CD) is associated with malnutrition, an independent risk factor for surgical morbidity and mortality in more than 65% of patients, with a significant impact on disease outcomes. In this single-center retrospective cohort study, we aimed to investigate the impact of total parenteral nutrition (TPN) on the surgical outcomes of patients with CD.Methods:
This study included patients with CD who underwent abdominal surgery. We compared patients who received preoperative total parenteral nutrition (TPN group) to those who did not (non-TPN group). Prolonged oral intolerance, albumin level <30 g/L, and body mass index <18.5 were the main indications for TPN. We evaluated postoperative surgical complications in both groups.Results:
Between January 2010 and October 2018, 169 eligible patients underwent abdominal surgery. The TPN and non-TPN groups included 40 and 129 patients, respectively. The mean albumin level was significantly lower in the TPN group (P = 0.013). Laparoscopic surgery was performed in 76.9% of the patients, with a conversion rate of 11.6%. Infectious and non-infectious complications developed in 8.9% and 16% of patients, respectively. Surgical complications were comparable between the groups (P >0.05).Conclusions:
Despite oral intake intolerance and severe disease in the TPN group, the surgical complications were comparable between the groups.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doença de Crohn
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article