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A novel HDAC6 inhibitor, CKD-504, is effective in treating preclinical models of huntington's disease.
Li, Endan; Choi, Jiwoo; Sim, Hye-Ri; Kim, Jiyeon; Jun, Jae Hyun; Kyung, Jangbeen; Ha, Nina; Kim, Semi; Ryu, Keun Ho; Chung, Seung Soo; Kim, Hyun Sook; Lee, Sungsu; Seol, Wongi; Song, Jihwan.
Afiliação
  • Li E; Department of Biomedical Science, CHA University, Seongnam 13488, Korea.
  • Choi J; Department of Biomedical Science, CHA University, Seongnam 13488, Korea.
  • Sim HR; CKD Research Institute, Chong Kun Dang Pharmaceutical Corp., Yongin 16995, Korea.
  • Kim J; Department of Biomedical Science, CHA University, Seongnam 13488, Korea.
  • Jun JH; CKD Research Institute, Chong Kun Dang Pharmaceutical Corp., Yongin 16995, Korea.
  • Kyung J; CKD Research Institute, Chong Kun Dang Pharmaceutical Corp., Yongin 16995, Korea.
  • Ha N; CKD Research Institute, Chong Kun Dang Pharmaceutical Corp., Yongin 16995, Korea.
  • Kim S; CKD Research Institute, Chong Kun Dang Pharmaceutical Corp., Yongin 16995, Korea.
  • Ryu KH; CKD Research Institute, Chong Kun Dang Pharmaceutical Corp., Yongin 16995, Korea.
  • Chung SS; Department of Physiology, Yonsei University College of Medicine, Seoul 03722, Korea.
  • Kim HS; Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
  • Lee S; iPS Bio Inc., Seongnam 13488, Korea.
  • Seol W; iPS Bio Inc., Seongnam 13488, Korea.
  • Song J; Department of Biomedical Science, CHA University, Seongnam 13488; iPS Bio Inc., Seongnam 13488, Korea.
BMB Rep ; 56(2): 178-183, 2023 Mar.
Article em En | MEDLINE | ID: mdl-36593104
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington Idioma: En Ano de publicação: 2023 Tipo de documento: Article