Canagliflozin Pretreatment Attenuates Myocardial Dysfunction and Improves Postcardiac Arrest Outcomes After Cardiac Arrest and Cardiopulmonary Resuscitation in Mice.

Ju, Feng; Abbott, Geoffrey W; Li, Jiaxue; Wang, Qifeng; Liu, Ting; Liu, Quanhua; Hu, Zhaoyang

Ju, Feng; Abbott, Geoffrey W; Li, Jiaxue; Wang, Qifeng; Liu, Ting; Liu, Quanhua; Hu, Zhaoyang.

Afiliação

Ju F; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Abbott GW; Bioelectricity Laboratory, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, CA, USA.
Li J; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wang Q; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Liu T; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Liu Q; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Hu Z; Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China. zyhu@hotmail.com.

Cardiovasc Drugs Ther ; 38(2): 279-295, 2024 Apr.

Article em En | MEDLINE | ID: mdl-36609949

Assuntos

Cardiomiopatias; Reanimação Cardiopulmonar; Diabetes Mellitus Tipo 2; Parada Cardíaca; Animais; Humanos; Masculino; Camundongos; Canagliflozina/farmacologia; Modelos Animais de Doenças; Volume Sistólico; Função Ventricular Esquerda

Palavras-chave

Canagliflozin; Cardiac arrest; Cardiopulmonary resuscitation; STAT-3; Sodium-glucose co-transporter 2 (SGLT-2) inhibitors

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reanimação Cardiopulmonar / Diabetes Mellitus Tipo 2 / Parada Cardíaca / Cardiomiopatias Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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