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Discovery of new quinoline and isatine derivatives as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative, docking and MD simulation studies.
Taghour, Mohammed S; Elkady, Hazem; Eldehna, Wagdy M; El-Deeb, Nehal; Kenawy, Ahmed M; Abd El-Wahab, Abeer E; Elkaeed, Eslam B; Alsfouk, Bshra A; Metwaly, Ahmed M; Eissa, Ibrahim H.
Afiliação
  • Taghour MS; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
  • Elkady H; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
  • Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • El-Deeb N; Biopharmaceutical Products Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.
  • Kenawy AM; Pharmaceutical and Fermentation Industries Development Center, City of Scientific Research and Technological Applications (SRTA city), Alexandria, Egypt.
  • Abd El-Wahab AE; Nucleic Acids Research Department, Genetic Engineering and Biotechnology Research Institute. City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.
  • Elkaeed EB; Pharmaceutical and Fermentation Industries Development Center, City of Scientific Research and Technological Applications (SRTA city), Alexandria, Egypt.
  • Alsfouk BA; Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.
  • Metwaly AM; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia.
  • Eissa IH; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
J Biomol Struct Dyn ; 41(21): 11535-11550, 2023.
Article em En | MEDLINE | ID: mdl-36617888
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolinas / Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article