X-ray energy spectrum estimation based on a virtual computed tomography system.

This paper presents a method for estimating the x-ray energy spectrum for computed tomography (CT) in the diagnostic energy range from the reconstructed CT image itself. To this end, a virtual CT system was developed, and datasets, including CT images for the Gammex phantom labeled by the corresponding energy spectra, were generated. Using these datasets, an artificial neural network (ANN) model was trained to reproduce the energy spectrum from the CT values in the Gammex inserts. In the actual application, an aluminum-based bow-tie filter was used in the virtual CT system, and an ANN model with a bow-tie filter was also developed. Both ANN models without/with a bow-tie filter can estimate the x-ray spectrum within the agreement, which is defined as one minus the absolute error, of more than 80% on average. The agreement increases as the tube voltage increases. The estimation was occasionally inaccurate when the amount of noise on the CT image was considerable. Image quality with a signal-to-noise ratio of more than 10 for the basis material of the Gammex phantom was required to predict the spectrum accurately. Based on the experimental data acquired from Activion16 (Canon Medical System, Japan), the ANN model with a bow-tie filter produced a reasonable energy spectrum by simultaneous optimization of the shape of the bow-tie filter. The present method requires a CT image for the Gammex phantom only, and no special setup, thus it is expected to be readily applied in clinical applications, such as beam hardening reduction, CT dose management, and material decomposition, all of which require exact information on the x-ray energy spectrum.