Development of a QuEChERS method for simultaneous analysis of 3-Monochloropropane-1,2-diol monoesters and Glycidyl esters in edible oils and margarine by LC-APCI-MS/MS.
Anal Chim Acta
; 1239: 340712, 2023 Jan 25.
Article
em En
| MEDLINE
| ID: mdl-36628717
ABSTRACT
A simple, fast and effective direct method based on HPLC-APCI-QqQ-MS/MS has been developed to simultaneously determine four 3-monochloropropane-1,2-diol monoesters (3-MCPDE) esterified with palmitic, linoleic, stearic, and oleic acid, and two glycidyl esters (GE) with palmitic and oleic acid in margarine and olive oil using a QuEChERS approach. Factors affecting the efficiency of the extraction process were assessed, including type and amount of salt, extraction solvent, test portion amount, and clean-up sorbent. The analytical method was validated according to Food and Drug Administration (FDA) guidelines using matrix-matched calibration with internal standards and showed good results in terms of linearity (r2 > 0.9992), accuracy (80Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alfa-Cloridrina
/
Espectrometria de Massas em Tandem
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article