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Initiative of clinical single-cell biomedicine in clinical and translational medicine.
Liu, Fangming; Liu, Xuanqi; Powell, Charles A; Chen, Chengshui; Zeng, Yiming; Fang, Hao; Wang, Xiangdong.
Afiliação
  • Liu F; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Institute of Clinical Bioinformatics, Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Fudan University Shanghai Medical College, Shanghai, China.
  • Liu X; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Institute of Clinical Bioinformatics, Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Fudan University Shanghai Medical College, Shanghai, China.
  • Powell CA; Division of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
  • Chen C; Quzhou People's Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, China.
  • Zeng Y; Center of Molecular Diagnosis and Therapy, The Second Hospital of Fujian Medical University, Quanzhou, China.
  • Fang H; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Wang X; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Institute of Clinical Bioinformatics, Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Fudan University Shanghai Medical College, Shanghai, China.
Clin Transl Med ; 13(1): e1173, 2023 01.
Article em En | MEDLINE | ID: mdl-36629041
ABSTRACT
With rapid developments of single-cell sequencing and multi/trans-omics, clinical single-cell biomedicine is a new and emergent discipline to integrate single-cell molecular and clinical phenomes and uncover new disease-specific diagnoses and therapy. The journal of Clinical and Translational Medicine (CTM) launches the first CTM initiative of clinical single-cell biomedicine (cscBioMed) to promote the discovery and development of single-cell-based biology and medicine, speed the translation from single-cell biology into clinical application, and improve early diagnosis and therapy for human diseases. The cscBioMed initiative is speeding translational processes from circulating single-cell RNA sequencing into routine measures in clinical biochemistry of haematology, from spatial transcriptomics into single-cell pathology, and from single-cell-based biomarkers and targets into clinical diagnostics and target drugs. With a clear goal, we expect that cscBioMed will benefit human health by establishing a clinical single-cell dynamic monitoring and early predicting system and by improving diagnosis and treatment.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciência Translacional Biomédica Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciência Translacional Biomédica Idioma: En Ano de publicação: 2023 Tipo de documento: Article