Cerebral foreign body granulomas after mechanical thrombectomy: Two case reports and a review of the literature.
J Stroke Cerebrovasc Dis
; 32(3): 106990, 2023 Mar.
Article
em En
| MEDLINE
| ID: mdl-36640722
ABSTRACT
OBJECTIVES:
A foreign body granuloma after an endovascular intervention is a rare complication. Some cases of foreign body granulomas, especially after coil embolization, have been reported. However, only four cases of foreign body granulomas after mechanical thrombectomy (MT) have previously been reported. The current study reports two cases of post-MT foreign body granulomas, including a biopsy-proven case. MATERIAL ANDMETHODS:
Case 1 A 73-year-old woman presented with complete occlusion of the right middle cerebral artery. Cerebral angiography and MT were successfully performed with improvement in clinical symptoms. Left hemiparesis and a disturbance in attention appeared after discharge and progressed slowly. She was re-admitted to our hospital 120 days after cerebral infarction owing to foreign body granulomas diagnosed on biopsy. Case 2 A 78-year-old man presented with occlusion of the left cervical internal carotid artery and the left middle cerebral artery. Cerebral angiography, percutaneous transluminal angioplasty, and MT were successfully performed. On the 34th day, he experienced progressive consciousness disorder because of foreign body granulomas. Both cases were successfully treated with steroid therapy.RESULTS:
MRI after steroid treatment showed the disappearance of most nodular lesions and improvement of the encephalopathy.CONCLUSIONS:
The cause of the granuloma may be an allergic reaction to the hydrophilic polymers that peel from endovascular devices. Steroid therapy is an effective treatment; therefore, neurologists should consider this complication when neurological symptoms or signs on image appears or worsens. A reliable diagnosis is important for prompt treatment.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Granuloma de Corpo Estranho
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article