Therapeutical impacts of transcranial direct current stimulation on drug-resistant epilepsy in pediatric patients: A double-blind parallel-group randomized clinical trial.
Epilepsy Res
; 190: 107074, 2023 02.
Article
em En
| MEDLINE
| ID: mdl-36657251
ABSTRACT
BACKGROUND:
Drug-resistant epilepsy is a challenging problem in pediatrics. Transcranial direct current stimulation (TDCS) is a non-invasive neurostimulation technique suggested as a promising method for treating epilepsy. This study aims to evaluate the efficacy of TDCS in focal epilepsy in children with drug-resistant epilepsy.METHOD:
We conducted a randomized sham-controlled study with 18 subjects between 6 and 16 years of age, divided equally into two groups. TDCS was performed in 20-minute daily stimulation protocol for five days for both groups. The current intensity was one mA for the first three days, increasing to 1.5 mA on day four and 2 mA on the last day of stimulation. EEG was done before and after the intervention.RESULTS:
There was a significant reduction in seizure duration in the case group compared with the sham group.CONCLUSION:
five consecutive days of performing TDCS significantly reduced seizure duration in children with focal Drug-resistant epilepsy. However,further studies in this field are necessary to test the effectiveness and set up a coherent and comprehensive protocol.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Epilepsias Parciais
/
Estimulação Transcraniana por Corrente Contínua
/
Epilepsia Resistente a Medicamentos
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article