Mutant plasminogen in hereditary angioedema is bypassing FXII/kallikrein to generate bradykinin.

Hintze, Stefan; Möhl, Britta S; Beyerl, Jessica; Wulff, Karin; Wieser, Andreas; Bork, Konrad; Meinke, Peter.

Afiliação

Hintze S; Friedrich-Baur-Institute at the Department of Neurology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
Möhl BS; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection and Pandemic Research, Munich, Germany.
Beyerl J; Institute of Virology, School of Medicine, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany.
Wulff K; Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
Wieser A; Max-von-Pettenkofer Institute, Ludwig-Maximilians-University Munich, Munich, Germany.
Bork K; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection and Pandemic Research, Munich, Germany.
Meinke P; University Medicine, University of Greifswald, Greifswald, Germany.

Front Physiol ; 13: 1090732, 2022.

Article em En | MEDLINE | ID: mdl-36685169