Design, synthesis, and in vitro cytotoxicity evaluation of novel dihydroartemisinin-isatin hybrids tethered via different length of esters as potential anti-breast cancer agents.

Xu, Zhi; Pan, Bowen; Chen, Linzhi; Xu, Dan

Xu, Zhi; Pan, Bowen; Chen, Linzhi; Xu, Dan.

Afiliação

Xu Z; School of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550025, PR China. Electronic address: chemorgchem@126.com.
Pan B; School of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550025, PR China.
Chen L; School of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550025, PR China.
Xu D; School of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550025, PR China.

Fitoterapia ; 166: 105436, 2023 Apr.

Article em En | MEDLINE | ID: mdl-36693438

Assuntos

Antineoplásicos; Artemisininas; Isatina; Neoplasias; Humanos; Estrutura Molecular; Isatina/farmacologia; Relação Estrutura-Atividade; Artemisininas/farmacologia; Antineoplásicos/farmacologia; Proliferação de Células; Ensaios de Seleção de Medicamentos Antitumorais; Linhagem Celular Tumoral; Desenho de Fármacos

Palavras-chave

Breast cancer; Dihydroartemisinin; Hybrid molecules; Isatin; Structure-activity relationship

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artemisininas / Isatina / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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