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Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation.
Spanjaard, Aldo; Stratigopoulou, Maria; de Groot, Daniël; Aslam, Muhammad; van den Berk, Paul C M; Stappenbelt, Chantal; Ayidah, Matilda; Catsman, Joyce J I; Pardieck, Iris N; Kreft, Maaike; Arens, Ramon; Guikema, Jeroen E J; Jacobs, Heinz.
Afiliação
  • Spanjaard A; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.
  • Stratigopoulou M; Department of Pathology, Amsterdam University Medical Centers, Location Academic Medical Center (AMC), Lymphoma and Myeloma center Amsterdam (LYMMCARE), Amsterdam, Netherlands.
  • de Groot D; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.
  • Aslam M; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.
  • van den Berk PCM; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.
  • Stappenbelt C; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.
  • Ayidah M; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.
  • Catsman JJI; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.
  • Pardieck IN; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.
  • Kreft M; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.
  • Arens R; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.
  • Guikema JEJ; Department of Pathology, Amsterdam University Medical Centers, Location Academic Medical Center (AMC), Lymphoma and Myeloma center Amsterdam (LYMMCARE), Amsterdam, Netherlands.
  • Jacobs H; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.
Front Immunol ; 13: 986863, 2022.
Article em En | MEDLINE | ID: mdl-36700204

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Switching de Imunoglobulina / Hipermutação Somática de Imunoglobulina Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Switching de Imunoglobulina / Hipermutação Somática de Imunoglobulina Idioma: En Ano de publicação: 2022 Tipo de documento: Article